The $4.8 million study will look at the potential benefits of treating men with testosterone supplements in conjunction with a dedicated weight-loss program through Weight Watchers.
Up to 1500 Australian men most at risk of developing type 2 diabetes, aged 50-74, are now being recruited to join the study in the States of South Australia, Victoria, New South Wales and Western Australia.
"We know that as men get older and gain weight -- especially when they become large around the belly -- they often suffer from reduced testosterone levels," says the leader of the study, Professor Gary Wittert from the University of Adelaide's School of Medicine.
"Lower testosterone has many implications for men's health, such as reduced motivation to exercise and lack of sexual function. It is also closely associated with type 2 diabetes, which is an enormous health burden for Australia.
"By giving testosterone supplements to men in that critical pre-diabetes stage, and by putting them on a dedicated weight-loss program, we expect to see sustained reductions in weight and a reduced chance to develop type 2 diabetes."
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